Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers.
作者： Elaine E Storm , Sonia Garel , Ugo Borello , Jean M Hebert , Salvador Martinez
DOI: 10.1242/DEV.02324
关键词: FOXG1 、 Genetics 、 Programmed cell death 、 FGF8 、 Phenotype 、 Forebrain 、 Fibroblast growth factor 、 Cell biology 、 Biology 、 Transcription factor 、 Cell growth
摘要: Mouse embryos bearing hypomorphic and conditional null Fgf8mutations have small and abnormally patterned telencephalons. We provide evidence that the hypoplasia results from …
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