Malignant melanoma of the foot and ankle

作者: P T Fortin , A A Freiberg , R Rees , V K Sondak , T M Johnson

DOI: 10.2106/00004623-199509000-00016

关键词: Foot (unit)ParonychiaPyogenic granulomaMedicineSurvival rateSurgeryGanglion cystAnkleLesionPrimary tumor

摘要: The records of sixty patients who had a malignant melanoma the foot or ankle were reviewed retrospectively to determine clinical features, prognostic factors, and distinguishing characteristics. Fifty-seven white three black. There forty-two women eighteen men (a female-to-male ratio 2.3 1). mean age at time presentation was fifty-seven years (range, twenty-two eighty-three years). most common site involvement plantar aspect foot. duration follow-up forty-five months 144 months). Kaplan-Meier life-table analysis revealed an over-all five-year survival rate 63 per cent ten-year 51 cent. for subungual lesion significantly shorter than that another on dorsal (forty-seven compared with seventy-two months) (p = 0.02). depth lesion, according criteria Breslow, 3.03 millimeters, level, classification Clark et al., IV. According American Joint Commission Cancer, forty-three stage-I II (local) disease, thirteen stage-III disease (nodal in-transit defined as cutaneous subcutaneous metastases more two centimeters from primary tumor but not beyond regional lymph nodes), four stage-IV (distant visceral metastases) presentation. Lesions sites also associated higher prevalence misdiagnosis lesions misdiagnoses included benign nevus (one patient), paronychia pyogenic granuloma (two patients), wart (three ganglion cyst blister traumatic (five patients).(ABSTRACT TRUNCATED AT 250 WORDS)

参考文章(27)
Calvin L. Day, Arthur J. Sober, Alfred W. Kopf, Robert A. Lew, Martin C. Mihm, Frederick M. Golomb, Allen Postel, Patrick Hennessey, Matthew N. Harris, Stephen L. Gumport, John W. Raker, Ronald A. Malt, A.Benedict Cosimi, William C. Wood, Daniel F. Roses, Fred Gorstein, Thomas B. Fitzpatrick, A prognostic model for clinical stage I melanoma of the trunk. Location near the midline is not an independent risk factor for recurrent disease. American Journal of Surgery. ,vol. 142, pp. 247- 251 ,(1981) , 10.1016/0002-9610(81)90286-5
B C Barnes, H F Seigler, T S Saxby, M S Kocher, J M Harrelson, Melanoma of the foot. Journal of Bone and Joint Surgery, American Volume. ,vol. 76, pp. 892- 898 ,(1994) , 10.2106/00004623-199406000-00013
Ann J. Worth, Richard P. Gallagher, J. Mark Elwood, Paul C. Yang, Charles Lamb, John J. Spinelli, William S. Wood, William J. Threlfall, Gerry B. Hill, Pathologic prognostic factors for cutaneous malignant melanoma: the Western Canada Melanoma Study. International Journal of Cancer. ,vol. 43, pp. 370- 375 ,(1989) , 10.1002/IJC.2910430303
Vincent C. Ho, Arthur J. Sober, Therapy for cutaneous melanoma: an update. Journal of The American Academy of Dermatology. ,vol. 22, pp. 159- 176 ,(1990) , 10.1016/0190-9622(90)70019-E
E. P. Der Van Esch, Natale Cascinelli, Ferdinando Preda, Alberto Morabito, Rosaria Bufalino, Stage I melanoma of the skin: Evaluation of prognosis according to histologic characteristics Cancer. ,vol. 48, pp. 1668- 1673 ,(1981) , 10.1002/1097-0142(19811001)48:7<1668::AID-CNCR2820480732>3.0.CO;2-9
Charles M. Balch, Marshall M. Urist, Constantine P. Karakousis, Thomas J. Smith, Walley J. Temple, Kristopher Drzewiecki, William R. Jewell, Alfred A. Bartolucci, Martin C. Mihm, Raymond Barnhill, Harold J. Wanebo, Efficacy of 2-cm surgical margins for intermediate-thickness melanomas (1 to 4 mm). Results of a multi-institutional randomized surgical trial. Annals of Surgery. ,vol. 218, pp. 262- 269 ,(1993) , 10.1097/00000658-199309000-00005
H.S. Rigby, J.C. Briggs, Subungual melanoma: a clinico-pathological study of 24 cases. British Journal of Plastic Surgery. ,vol. 45, pp. 275- 278 ,(1992) , 10.1016/0007-1226(92)90051-X
Gary S Rogers, Alfred W Kopf, Darrell S Rigel, Robert J Friedman, Jeffrey L Levine, Marcia Levenstein, Robert S Bart, Medwin M Mintzis, Effect of Anatomical Location on Prognosis in Patients With Clinical Stage I Melanoma Archives of Dermatology. ,vol. 119, pp. 644- 649 ,(1983) , 10.1001/ARCHDERM.1983.01650320018009