作者: Calvin L. Day , Arthur J. Sober , Alfred W. Kopf , Robert A. Lew , Martin C. Mihm
DOI: 10.1016/0002-9610(81)90286-5
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摘要: Abstract Fifteen variables were studied for their usefulness in predicting recurrent disease 254 patients with clinical stage I melanoma of the trunk. Thickness primary tumor correctly predicted outcome an accuracy 90 percent or greater 176 primaries a thickness less than 1.70 mm 5.5 greater. No other significantly increased predictive over these ranges thickness. A Cox proportional hazards analysis remaining 78 tumors to 5.49 thick demonstrated that following four functioned as independent risk factors disease: (1) (p = 0.0005), (2) mitoses/mm 2 >6 0.006), (3) nearly absent minimal lymphocyte response at base 0.009), and (4) location on upper trunk 0.03). Trunk lesions located near midline did not have worse prognosis more lateral melanomas similar