Prognostic Factors in Patients Undergoing Lymphadenectomy for Malignant Melanoma

摘要: Review of a 19 year experince in melanoma patients undergiong lymphadenectomy at the National Cancer Institute reveled that preoperative asesment staus regional lymph nodes was accurate 91% tme when surgeon felt were clinically positive, and 79% time judged negative. The 10-year survival with one to three histologically positive nodes. or 50–55%, compared 25% 8-year four more nods. Stepwise multivariate evaluation prognostic factors indicated most important factor for predicting prognosis is number involved. Node palpability second becuause its high correlation ivolved. because node palpabilty Site te third factor, as extremity (upper lower) had better (P = 0.002) than axial (trunk head neck). Five years following there appeared be substantial differences according level invasion primary lesion, however, these wer not nearly pronounced 10 dissection. division thicknesses into 1.50 mm provided some discrimiantion five but again thickness measurements esasier determine invasion, reproduceable on resubmission same pathologist. Four less 0.76 subsequent metastases, may repreent inadequate sampling both our series similar previosusly reported such thin metastasizing melanomas.