Therapeutic hypothermia after prolonged cardiopulmonary resuscitation for pulseless electrical activity.
作者： Reussen Em , Bartels M , Tjan Dh , van Zanten Ar
DOI:
关键词: Clinical death 、 Pulseless electrical activity 、 Medicine 、 Anesthesia 、 Return of spontaneous circulation 、 Hypothermia 、 Vascular disease 、 Pulmonary embolism 、 Cardiopulmonary resuscitation 、 Thrombolysis
摘要: We report an 18-year-old female patient with cardiac arrest due to pulseless electrical activity caused by a massive pulmonary embolism. Cardiopulmonary resuscitation was continued for more than one hour. Although the initial clinical signs and symptoms suggested poor outcome, immediate intravenous thrombolysis instituted. After return of spontaneous circulation (75 minutes) still comatose mild therapeutic hypothermia (32.5 degrees C) instituted brain protection during first 24 hours. She recovered uneventfully without neurological deficit. Therapeutic may be effective neuroprotection in non-VFcardiac arrest.
researchgate.net 参考文章(11)
R Busto, M Y Globus, W D Dietrich, E Martinez, I Valdés, M D Ginsberg, Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain. Stroke. ,vol. 20, pp. 904- 910 ,(1989) , 10.1161/01.STR.20.7.904
Hiroshi Karibe, Gregory J. Zarow, Steven H. Graham, Philip R. Weinstein, Mild intraischemic hypothermia reduces postischemic hyperperfusion, delayed postischemic hypoperfusion, blood-brain barrier disruption, brain edema, and neuronal damage volume after temporary focal cerebral ischemia in rats. Journal of Cerebral Blood Flow and Metabolism. ,vol. 14, pp. 620- 627 ,(1994) , 10.1038/JCBFM.1994.77
Michael Buist, Stephen A. Bernard, Induced hypothermia in critical care medicine: A review Critical Care Medicine. ,vol. 31, pp. 2041- 2051 ,(2003) , 10.1097/01.CCM.0000069731.18472.61
Arthur R. H. van Zanten, Kees H. Polderman, Early induction of hypothermia: will sooner be better? Critical Care Medicine. ,vol. 33, pp. 1449- 1452 ,(2005) , 10.1097/01.CCM.0000166710.64724.34
Kees H. Polderman, Keeping a cool head: How to induce and maintain hypothermia* Critical Care Medicine. ,vol. 32, pp. 2558- 2660 ,(2004) , 10.1097/01.CCM.0000148087.41418.0A
R O Cummins, D A Chamberlain, N S Abramson, M Allen, P J Baskett, L Becker, L Bossaert, H H Delooz, W F Dick, M S Eisenberg, Recommended guidelines for uniform reporting of data from out-of-hospital cardiac arrest: the Utstein Style. A statement for health professionals from a task force of the American Heart Association, the European Resuscitation Council, the Heart and Stroke Foundation of Canada, and the Australian Resuscitation Council. Circulation. ,vol. 84, pp. 960- 975 ,(1991) , 10.1161/01.CIR.84.2.960
Stephen A. Bernard, Timothy W. Gray, Michael D. Buist, Bruce M. Jones, William Silvester, Geoff Gutteridge, Karen Smith, Treatment of Comatose Survivors of Out-of-Hospital Cardiac Arrest with Induced Hypothermia The New England Journal of Medicine. ,vol. 346, pp. 557- 563 ,(2002) , 10.1056/NEJMOA003289
R.A Waalewijn, R de Vos, R.W Koster, Out-of-hospital cardiac arrests in Amsterdam and its surrounding areas: results from the Amsterdam resuscitation study (ARREST) in Utstein style. Resuscitation. ,vol. 38, pp. 157- 167 ,(1998) , 10.1016/S0300-9572(98)00102-6
Per Vaagenes, Myron Ginsberg, Uwe Ebmeyer, Lars Ernster, Matthias Fischer, Sven-Erik Gisvold, Alexander Gurvitch, Konstantin A. Hossmann, Edwin M. Nemoto, Ann Radovsky, John W. Severinghaus, Peter Safar, Robert Schlichtig, Fritz Sterz, Tor Tonnessen, Robert J. White, Feng Xiao, Yuan Zhou, Cerebral resuscitation from cardiac arrest: pathophysiologic mechanisms. Critical Care Medicine. ,vol. 24, ,(1996) , 10.1097/00003246-199602000-00048
Michael Holzer, Stephen A Bernard, Said Hachimi-Idrissi, Risto O Roine, Fritz Sterz, Marcus Müllner, Collaborative Group on Induced Hypothermia for Neuroprotection After Cardiac Arrest, Hypothermia for neuroprotection after cardiac arrest: systematic review and individual patient data meta-analysis. Critical Care Medicine. ,vol. 33, pp. 414- 418 ,(2005) , 10.1097/01.CCM.0000153410.87750.53