CD163 promotes hematoma absorption and improves neurological functions in patients with intracerebral hemorrhage

作者: Qun Liu , Hong-mei Meng , Wen-jing Xie , Hong-quan Yu , Yu Zhang

DOI: 10.4103/1673-5374.187047

关键词: HaptoglobinModified Rankin ScaleAbsorption (skin)Intracerebral hemorrhageCD163AnesthesiaMedicineHematomaHemoglobinScavenger receptor

摘要: Clinical outcomes are positively associated with hematoma absorption. The monocyte-macrophage scavenger receptor, CD163, plays an important role in the metabolism of hemoglobin, and a soluble form CD163 is present plasma other tissue fluids; therefore, we speculated that serum affects absorption after intracerebral hemorrhage. Patients hemorrhage were divided into high- low-level groups according to average level (1,977.79 ± 832.91 ng/mL). Compared high-level group, group had significantly slower rate, increased National Institutes Health Stroke Scale scores modified Rankin scores. These results suggest promotes recovery neurological function patients

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