Uterine rupture and dehiscence associated with intravaginal misoprostol cervical ripening

摘要: Objective To evaluate if the prostaglandin E1 analogue misoprostol, when used as an agent for cervical ripening, is associated with uterine rupture. Study design We performed a two-year retrospective chart review to determine incidence of rupture in patients previous cesarean delivery undergoing ripening or induction labor. Results Uterine dehiscence occurred 1 and 3 48 women prior treated 50 micrograms doses intravaginal misoprostol ripening. was found 89 who had oxytocin infusion labor none 24 received E2 placed Conclusion Intravaginal appears be increased trial after cesarean.