Rapid detection of Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) in wound specimens and blood cultures: Multicenter preclinical evaluation of the cepheid Xpert MRSA/SA skin and soft tissue and blood culture assays

作者: D. M. Wolk , M. J. Struelens , P. Pancholi , T. Davis , P. Della-Latta

DOI: 10.1128/JCM.01884-08

关键词: Blood cultureMicrobiologyMeticillinDrug resistanceMedicineAntibioticsSoft tissueStaphylococcus aureusRapid detectionMicrococcaceae

摘要: A multicenter preclinical evaluation was conducted to evaluate the performance of two Cepheid Xpert assays for detection methicillin-resistant Staphylococcus aureus (MRSA) and S. aureus. Sensitivity 97.1% 98.3% MRSA in wound blood culture specimens, respectively. 100% from both specimen types.

参考文章(18)
P. Francois, M. Bento, G. Renzi, S. Harbarth, D. Pittet, J. Schrenzel, Evaluation of Three Molecular Assays for Rapid Identification of Methicillin-Resistant Staphylococcus aureus Journal of Clinical Microbiology. ,vol. 45, pp. 2011- 2013 ,(2007) , 10.1128/JCM.00232-07
Yuki Katayama, Hong-Zhong Zhang, Henry F. Chambers, PBP 2a Mutations Producing Very-High-Level Resistance to Beta-Lactams Antimicrobial Agents and Chemotherapy. ,vol. 48, pp. 453- 459 ,(2004) , 10.1128/AAC.48.2.453-459.2004
L. G. Miller, C. Quan, A. Shay, K. Mostafaie, K. Bharadwa, N. Tan, K. Matayoshi, J. Cronin, J. Tan, G. Tagudar, A. S. Bayer, A Prospective Investigation of Outcomes after Hospital Discharge for Endemic, Community-Acquired Methicillin-Resistant and -Susceptible Staphylococcus aureus Skin Infection Clinical Infectious Diseases. ,vol. 44, pp. 483- 492 ,(2007) , 10.1086/511041
Teruyo ITO, Kyoko KUWAHARA, Ken HISATA, Keiko OKUMA, Longzhu CUI, Keiichi HIRAMATSU, [Community-associated methicillin-resistant Staphylococcus aureus: current status and molecular epidemiological perspective]. The Journal of the Japanese Association for Infectious Diseases. ,vol. 78, pp. 459- 469 ,(2004) , 10.11150/KANSENSHOGAKUZASSHI1970.78.459
Frances A. Griffin, Reducing Methicillin-Resistant Staphylococcus aureus (MRSA) Infections The Joint Commission Journal on Quality and Patient Safety. ,vol. 33, pp. 726- 731 ,(2007) , 10.1016/S1553-7250(07)33087-0
Hhs Office for Civil Rights, Standards for privacy of individually identifiable health information. Final rule. Federal Register. ,vol. 67, pp. 53181- 53273 ,(2002)
Donna M. Hacek, Lance R. Peterson, Ari Robicsek, 5 Million Lives Campaign ,(2008)
W. Witte, B. Pasemann, C. Cuny, Detection of low-level oxacillin resistance in mecA-positive Staphylococcus aureus Clinical Microbiology and Infection. ,vol. 13, pp. 408- 412 ,(2007) , 10.1111/J.1469-0691.2006.01671.X