Impact of diabetes mellitus on long-term clinical outcomes of patients on chronic hemodialysis after percutaneous coronary intervention.

作者: GABRIEL L. SARDI , GABRIEL MALUENDA , REBECCA TORGUSON , ZHENYI XUE , WILLIAM O. SUDDATH

DOI: 10.1111/J.1540-8183.2011.00682.X

关键词: Conventional PCIInternal medicineDiabetic angiopathySurgeryPercutaneous coronary interventionMortality ratePopulationMaceDiabetes mellitusRevascularizationMedicine

摘要: Background:End-stage renal disease (ESRD) is known to correlate with poor outcome in patients undergoing percutaneous coronary intervention (PCI). This study examines the impact of diabetes mellitus (DM) on long-term ESRD chronic hemodialysis. Methods:A cohort hemodialysis, who underwent PCI drug-eluting stents, was followed for 1 year. The clinical this population compared retrospectively based presence DM. Major adverse cardiac events (MACE) as composite all-cause death, Q-wave myocardial infraction and target lesion revascularization (TLR), well TLR an individual outcome, were main end points study. Results:In (n = 198), 48.5% had Diabetic more commonly female. characteristics similar between groups except frequent saphenous vein graft nondiabetics. At 1-year follow-up there no difference rate MACE diabetic nondiabetic (40.4% vs. 39.3%, respectively, p 0.89), driven primarily by a very high mortality (1-year overall 33.5%). After adjustment relevant co-variables, DM not associated point. However, significantly higher incidence nondiabetics (13.8% 3.6%, 0.04). Conclusion:The prognosis after dismal regardless Patients appear be at risk need revascularization. (J Interven Cardiol 2012;25:147–155)

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