Influence of hemodialysis duration on mid-term clinical outcomes in hemodialysis patients with coronary artery disease after drug-eluting stent implantation

摘要: Accelerated atherosclerosis in prolonged maintenance hemodialysis (HD) has been recognized; however, whether HD duration is associated with poor clinical outcome patients coronary artery disease (CAD) after drug-eluting stent (DES) implantation unknown. We evaluated the impact of on outcomes CAD DES implantation. Between April 2007 and December 2012, 168 angina pectoris (320 de novo lesions) were treated DES. Major adverse cardiovascular events (MACE) target lesion revascularization (TLR) investigated at 3 years according to (≤ years, 83 patients; >3 85 patients). The incidence MACE was significantly higher long group (25.3 vs. 50.6 %; P = 0.001). Especially, sudden cardiac death (SCD) (3.6 16.5 0.006). On other hand, rates TLR similar between two groups (12.0 14.1 0.69). Cox's proportional hazard analysis revealed that (HR 1.08 per year, 95 % CI 1.03-1.13, 0.002), β-blocker use (0.28, 0.17-0.46, < 0.001), diabetes mellitus (2.10, 1.23-3.56, 0.007) independent predictors MACE. Longer did not affect TLR; SCD group.