Comparison of haemodialysis patients and non-haemodialysis patients with respect to clinical characteristics and 3 year clinical outcomes after sirolimus-eluting stent implantation: insights from the Japan multi-centre post-marketing surveillance registry

摘要: Aims Long-term outcomes after sirolimus-eluting stent (SES) implantation in haemodialysis (HD) patients have remained controversial. We investigated the impact of HD on SES implantation. Methods and results analysed data 2050 who underwent a multi-centre prospective registry Japan. Three-year clinical were compared between group ( n = 106) non-haemodialysis (NH) 1944). At 3 year follow-up, rates unadjusted cardiac mortality (HD: 16.3 vs. NH: 2.3%) target-lesion revascularization (TLR) 19.4 6.6%) significantly higher than NH P < 0.001). Although had numerically thrombosis rate, difference two groups 2.0 0.7%) did not reach statistical significance. Using Cox's proportional-hazard models with propensity score adjustment for baseline differences, risks TLR [HD: 6.1%; hazard ratio, 2.83; 95% confidence interval (CI): 1.62–4.93, 0.0003] death 12.3 2.3%; 5.51; CI: 2.58–11.78, 0.0001). The consistent analyses, whether or adjusted other procedural identify as an independent risk factor TLR. Conclusions Percutaneous coronary intervention has incidence repeat those patients. Haemodialysis appears to be strongly associated even implantation.