Corticosteroids in Neuro-Oncology

作者: Nina A. Paleologos , Nicholas A. Vick

DOI: 10.1007/978-1-59259-317-0_3

关键词: Peritumoral Brain EdemaBrain edemaBrain tumorSteroid MyopathyMedicineVasogenic edemaIntensive care medicineNeuro oncology

摘要: This chapter has two distinct parts. The first will deal with the clinical aspects of use corticosteroids in neuro-oncology. second review what is known biological basis remarkable effects this class drugs upon peritumoral brain edema. Unfortunately, despite decades work, we still know all too little. Most do clinically empirical. absence a full understanding their mechanism action blocked search for similar benefit but that lack troublesome side effects. Nonetheless, deficiency our how steroids work does not detract from tremendous impact had care patients tumors since they were introduced control tumor-induced edema nearly 40 years ago.

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