Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation
作者： Dahvid Davda , Brent R. Martin
DOI: 10.1039/C3MD00333G
关键词: Protein palmitoylation 、 Proteome 、 Serine hydrolase 、 Biochemistry 、 Palmitoylation 、 Thioester 、 Enzyme 、 Cysteine 、 Thioesterase 、 Biology
摘要: … We hypothesized that any candidate thioesterase is likely a serine hydrolase inhibited by HDFP… , and directly reacts with APT1 and APT2 as both a substrate and an inhibitor in live cells. …
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