Chronic Granulomatous Disease; fundamental stages in our understanding of CGD

摘要: It has been 50 years since chronic granulomatous disease was first reported as a which fatally affected the ability of children to survive infections. Various milestone discoveries from insufficient patients' leucocytes destroy microbial particles underlying genetic predispositions through is inherited have had important consequences. Longterm antibiotic prophylaxis helped fight infections associated with while steady progress in bone marrow transplantation and prospect gene therapy are hailed long awaited permanent treatment options. This review unearths findings by scientists that led our current understanding disease.