Uncontrolled blood pressure and risk of sleep apnea among blacks: findings from the Metabolic Syndrome Outcome (MetSO) study.

作者: A Seixas , J Ravenell , N J Williams , S K Williams , F Zizi

DOI: 10.1038/JHH.2015.78

关键词: MedicineMetabolic syndromeDyslipidemiaBlood pressureSleep apneaOdds ratioInternal medicineObstructive sleep apneaCohort studyPhysical therapyApnea

摘要: Uncontrolled blood pressure (BP) is linked to increased risk of obstructive sleep apnea (OSA). However, few studies have assessed the impact this relationship among blacks with metabolic syndrome (MetS). Data for study were collected from 1035 (mean age=62±13 years) enrolled in Metabolic Syndrome Outcome study. Patients a score ⩾6 on Apnea Risk Evaluation System considered at OSA. Of sample, 77.1% low-to-high OSA and 92.3% hypertensive, which 16.8% had uncontrolled BP levels. Analysis also showed that 60.4% diabetic, 8.9% stroke history, 74.3% dyslipidemia, 69.8% obese 30.9% history heart disease. Logistic regression analyses employed investigate associations between risk, while adjusting known covariates. Findings independently odds twofold (odds ratio=2.02, 95% confidence interval=1.18-3.48, P<0.05). In conclusion, our findings show was associated greater blacks, suggesting those MetS who should be screened presence

参考文章(40)
Luciano F. Drager, Sônia M. Togeiro, Vsevolod Y. Polotsky, Geraldo Lorenzi-Filho, Obstructive Sleep Apnea: A Cardiometabolic Risk in Obesity and the Metabolic Syndrome Journal of the American College of Cardiology. ,vol. 62, pp. 569- 576 ,(2013) , 10.1016/J.JACC.2013.05.045
Terri E. Weaver, Nancy Barone Kribbs, Allan I. Pack, Lewis R. Kline, Deepak K. Chugh, Greg Maislin, Philip L. Smith, Alan R. Schwartz, Norman M. Schubert, Kelly A. Gillen, David F. Dinges, Night-to-night variability in CPAP use over the first three months of treatment Sleep. ,vol. 20, pp. 278- 283 ,(1997) , 10.1093/SLEEP/20.4.278
D A Sclar, M A Gill, T L Skaer, M P Okamoto, A Chin, R K Nakahiro, Effect of health education in promoting prescription refill compliance among patients with hypertension. Clinical Therapeutics. ,vol. 13, pp. 489- 495 ,(1991)
G Ogedegbe, Js Borer, Db Brown, F Zizi, G Jean-Louis, SI McFARLANE, Obstructive sleep apnea and cardiovascular disease: evidence and underlying mechanisms. Minerva pneumologica. ,vol. 48, pp. 277- 293 ,(2009)
Christopher J. Lettieri, Arn H. Eliasson, David L. Greenburg, Persistence of Obstructive Sleep Apnea After Surgical Weight Loss Journal of Clinical Sleep Medicine. ,vol. 04, pp. 333- 338 ,(2008) , 10.5664/JCSM.27233
G. M. Reaven, Pathophysiology of insulin resistance in human disease Physiological Reviews. ,vol. 75, pp. 473- 486 ,(1995) , 10.1152/PHYSREV.1995.75.3.473
A. R. Schwartz, S. P. Patil, A. M. Laffan, V. Polotsky, H. Schneider, P. L. Smith, Obesity and obstructive sleep apnea: pathogenic mechanisms and therapeutic approaches. Proceedings of the American Thoracic Society. ,vol. 5, pp. 185- 192 ,(2008) , 10.1513/PATS.200708-137MG