Asparagine Synthetase Expression and Phase I Study With L-Asparaginase Encapsulated in Red Blood Cells in Patients With Pancreatic Adenocarcinoma.
作者： Jean-Baptiste Bachet , Fabien Gay , Raphaël Maréchal , Marie-Pierre Galais , Antoine Adenis
DOI: 10.1097/MPA.0000000000000394
关键词: Asparagine synthetase 、 Medicine 、 Asparaginase 、 Immunohistochemistry 、 Drug 、 In patient 、 Cancer research 、 L asparaginase 、 Adenocarcinoma 、 Phase i study 、 Pathology
摘要: ObjectivesAsparaginase encapsulated in erythrocytes (ERY-ASP) is a potentially effective drug patients with pancreatic adenocarcinoma (PAC) null/low asparagine synthetase (ASNS) expression. Our aims were to assess ASNS expression PAC from large cohort and its prognostic and/or predictiv
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