Immunomodulatory effects of high-protein diet with resveratrol supplementation on radiation-induced acute-phase inflammation in rats.
作者： Kyoung-Ok Kim , HyunJin Park , Mison Chun , Hyun-Sook Kim
关键词: Resveratrol 、 Medicine 、 High-protein diet 、 Endocrinology 、 Inflammation 、 Internal medicine 、 Immunology 、 Proinflammatory cytokine 、 Triglyceride 、 Immune system 、 Lipid metabolism 、 Cytokine
摘要: Abstract We hypothesized that a high-protein diet and/or resveratrol supplementation will improve acute inflammatory responses in rats after receiving experimental abdominal radiation treatment (ART). Based on our previous study, the period of 10 days ART was used as an inflammation model. Rats were exposed to dose 17.5 Gy and supplied with control (C), 30% (HP), (RES), or HP RES ([HP+RES]). At day ART, we measured profiles lipids, proteins, immune cells blood. The levels clusters differentiating 4+ (CD4+) regulatory T cells, serum proinflammatory cytokines, 8-hydroxy-2′-deoxyguanosine (8-OHdG) urine also measured. caused significant disturbances lipid by increasing triglyceride (TG) low-density lipoprotein cholesterol (LDL-C), decreasing high-density cholesterol. proinflammatroy cytokine increased ART. All ...
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