Palladium-Catalyzed Annulation of Aryl Heterocycles with Strained Alkenes
作者： David G. Hulcoop , Mark Lautens
DOI: 10.1021/OL070475W
关键词: Annulation 、 Medicinal chemistry 、 Intramolecular force 、 Catalysis 、 Aryl 、 Intermolecular force 、 Palladium 、 Alkene 、 Chemistry 、 Halide
摘要: [reaction: see text] An annulation reaction proceeding by the intermolecular addition of an arylpalladium(II) halide across a strained alkene, followed intramolecular C-H functionalization pendant heterocycle is described. A variety polycyclic heterocycles have been prepared from readily accessible haloaryl with range alkene partners.
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