Lymphoblastic Lymphomas, Mouse

作者: Gerhard R. F. Krueger

DOI: 10.1007/978-3-642-84110-1_42

关键词: Lymphomatous infiltrationPathogenesisT-cell lymphomaGROSS LESIONLobePathologyThymic LymphomaLymphThymic atrophyBiology

摘要: Most lymphoblastic lymphomas of the mouse appear to originate in thymus, though not necessarily from thymic lymphocytes (see Etiology and Pathogenesis). The initial gross lesion is reduction size (thymic atrophy). Subsequently, one lobe enlarges by nodular lymphomatous infiltration which spreads progressively involve entire organ. At this time, thymus may measure up 1 cm diameter, yet also unremarkable thymuses can be entirely replaced leukemic cells (Fig. 282). organ pale-pink color, has a fish flesh appearance, friable. Subsequently enlarged lymph nodes exhibit similar changes.

参考文章(35)
G. R. F. Krueger, Comparative pathologic classification of malignant lymphomas. Zeitschrift für Krebsforschung. ,vol. 89, pp. 253- 272 ,(1977) , 10.1007/BF00283782
Gerhard R. F. Krueger, Abnormal Variation of the Immune System as Related to Cancer Springer, Dordrecht. pp. 139- 161 ,(1989) , 10.1007/978-94-009-2530-4_19
Israel Penn, Allograft Transplant cancer Registry Springer, Boston, MA. pp. 281- 308 ,(1984) , 10.1007/978-1-4684-4760-6_14
J. L. Cleveland, Y. Weinstein, J. N. Ihle, D. S. Askew, U. R. Rapp, Transformation and Insertional Mutagenesis In Vitro of Primary Hematopoietic Stem Cell Cultures Current Topics in Microbiology and Immunology. ,vol. 132, pp. 44- 54 ,(1986) , 10.1007/978-3-642-71562-4_7
Leo A. Phillips, Viruses associated with human cancer Marcel Dekker, Inc.. ,(1983)
David S. Yohn, Advances in comparative leukemia research M. Dekker. ,(1983)
Steven R. Tronick, Stuart A. Aaronson, Oncogenes, Growth Factors, and Receptors Concepts in Viral Pathogenesis II. pp. 98- 109 ,(1986) , 10.1007/978-1-4612-4958-0_12
J. Michael Bishop, Amplification of Proto-oncogenes in Tumorigenesis Concepts in Viral Pathogenesis II. pp. 71- 78 ,(1986) , 10.1007/978-1-4612-4958-0_9