The Relative Power of Family-Based and Case-Control Designs for Linkage Disequilibrium Studies of Complex Human Diseases I. DNA Pooling
作者： Neil Risch , Jun Teng
DOI: 10.1101/GR.8.12.1273
关键词: Genetics 、 Biology 、 Linkage disequilibrium 、 Statistics 、 Genotyping 、 Allele 、 Allele frequency 、 Locus (genetics) 、 Population stratification 、 Statistic 、 Nuclear family
摘要: … both DNA pooling and individual genotyping. As we describe, DNA pooling precludes the … Therefore, other values of Z α andZ 1 − β will give sample size ratios that are similar to those …
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