Prevention of T-2 toxin-induced morphologic effects in the rat by highly activated charcoal.

作者: Paula M. Bratich , William B. Buck , Wanda M. Haschek

DOI: 10.1007/BF02010733

关键词: SpleenStomachSmall intestineNecrosisBiologyInternal medicineToxicityCharcoalToxinEndocrinologyActivated charcoal

摘要: The efficacy of a highly activated charcoal in preventing the morphologic effects T-2 toxin was examined female rats. at 25 mg/kg (6×LD50) given orally to all Half rats also received charcoal, dose 9 ml/kg and concentration 104 mg/ ml, while other half water. A charcoal-treated rat (T-2 + charcoal) killed time death each positive control animal alone). Severe necrosis seen spleen, thymus, stomach, small intestine, liver adrenal glands controls Lesions were absent or minimal paired charcoal).

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