A Comparison of Intravaginal PGF2α and Intravenous Oxytocin to Stimulate Labour after Membrane Rupture
作者： Andrew Day , Alastair MacLennan , Roslyn Green
DOI: 10.1111/J.1479-828X.1985.TB00738.X
关键词: Pethidine 、 Anesthesia 、 Regimen 、 Intravenous therapy 、 Jaundice 、 Alpha (ethology) 、 Analgesic 、 Oxytocin 、 Medicine 、 Randomized controlled trial
摘要: A prospective randomized controlled trial of 202 patients was set up to examine the efficiency and safety 40 mg intravaginal prostaglandin F2 alpha (PGF2 alpha) in a tylose gel stimulate labour after artificial or spontaneous membrane rupture. The control group received standard intravenous oxytocin regimen. PGF2 treated had significantly shorter length (6.2 +/- 3.6 hours) compared (7.5 4.3 (p less than 0.05). analgesic requirements were reduced patients. In 46 105 required no analgesia whereas 17 97 0.001). There similar reductions for epidural 0.005) pethidine 0.005). No differences found between groups with regards mode delivery. adverse maternal side-effects associated usage. significant reduction 0.05) incidence neonatal jaundice requiring phototherapy occurred group. Prostaglandin appears be safe, efficient better alternative presence ruptured membranes, allowing ambulation, need therapy.
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