Indications and outcomes of surgical closure of ventricular septal defect in adults.

摘要: Objectives We sought to review our experience with surgical ventricular septal defect (VSD) closure in adults. Background Outcome data of VSD adults on which base recommendations are limited. Guidelines recommend adult for a Q p /Q s ratio ≥2, left volume overload, or endocarditis. Methods retrospectively reviewed 46 patients (mean age 33.6 ± 11.2 years, 24 women) who underwent (1958 2008). Results VSDs were classified according the Society Thoracic Surgeons as type 2 (membranous, 72%) 1 (subarterial, 26%). Aortic regurgitation (AR) (28%), dilation (20%), and pulmonary hypertension (20%) most common indications closure. Associated lesions justified surgery 39% patients. There no early deaths. Morbidity included high-grade atrioventricular block requiring permanent pacemaker residual 7 Late mortality was 5% follow-up: 10.3 12.4 years). Patient survival did not differ from expected reference population (p = 0.75). more after suture (6 8 patients). moderate AR developed 5 (4 VSD) aortic valve sinus Valsalva repair. The use intraoperative transesophageal echocardiography associated fewer less ≥ tricuspid AR. Conclusions heart defects adults, performed low morbidity. Patch improve outcomes. Important residua emphasize need life-long informed follow-up.