作者: Giampaolo Tomasi , Lula Rosso
DOI: 10.1016/J.COPH.2012.07.016
关键词: Tumour volume 、 Response to treatment 、 Pet imaging 、 Oncology 、 Molecular imaging 、 Tracer uptake 、 Therapy monitoring 、 Medicine 、 Neoplasms diagnosis 、 Internal medicine 、 Nuclear medicine 、 PET-CT
摘要: Among the methods based on molecular imaging, measure of tracer uptake variation between a baseline and follow-up scan with SUV [(18)F]FDG-PET/CT is very powerful tool for assessing response to treatment in oncology. However, development new targeted therapeutics tissue pharmacokinetic evaluation existing ones are increasingly requiring therapy monitoring alternative tracers indicators. In parallel, potential predictive prognostic value other image-derived parameters, such as tumour volume textural features, relating tumoral heterogeneity, has recently emerged from several works.