Management of Helicobacter pylori Infection

摘要: The discovery of Helicobacter pylori (H. pylori) in 1982 by Barry Marshall and Robin Warren was the starting point a new era understanding management gastroduodenal diseases. H. is spiral-shaped, gram-negative, microaerophilic, urease-producing bacterium. It one most common human infections worldwide, it estimated that about half world’s population infected [1]. risk acquiring infection related to socioeconomic status, living conditions, habits we acquire from early childhood. Person-to-person transmission through either fecal-to-oral or oral-to-oral exposure seems be probable way infection. In developing nations, where majority children are before age 10, prevalence adults exceeds 80% developed countries, detection unusual but becomes more during adulthood, increases up 50% elderly Approximately 30% 40% United States (US) with [2]. North America, among Asian Americans, African Hispanics similar found countries [3]. Once acquired, persists stomach for years may not produce disease. Over individuals bacterium asymptomatic. However, main factor broad variety chronic gastrointestinal diseases such as gastritis, peptic ulcer disease, gastric adenocarcinoma, mucosa-associated lymphoid tissue (MALT) lymphoma.