Analysis of cognitive dysfunction with silent cerebral infarction: a prospective study in Chinese patients.

摘要: To investigate the relationship between Silent Cerebral Infarction (SCI) and cognitive impairment to testify that Montreal Cognitive Assessment (MoCA) is a more sensitive screening tool than Mini Mental State Examination (MMSE) identify deficits in patients with SCI. We recruited 196 individuals Shanghai of China divided them into 2 groups: SCI group including 112 (45 men 67 women; aged from 43 70 years old) control 84 (43 41 42 79 old). collected information participants’ gender, age, blood glucose, kidney function, lipids, pressure, Electrocardiogram (ECG), carotid artery ultrasound, MMSE score, MoCA score. SAS software (version 9.1) was used perform statistical analysis on physical examinations outcomes participants. Furthermore, multiple logistic regression model built up screen out independent risk factors Besides, Receiver Operator Characteristic (ROC) also used. Multivariate showed abnormal ECG existence plaques were occurrence, while scores negatively associated risk. Moreover, might be valuable predicting vascular (VCI) (0.667 vs 0.626). found generally insensitive detect impairment; but has good balance sensitivity specificity at cut-score 26. accompany VCI appeared an excellent test for SCI, worthy being promoted clinical practitioning Chinese population.