Prevalence and Diversity of Small Mammal-Associated Bartonella Species in Rural and Urban Kenya

作者: Jo E. B. Halliday , Darryn L. Knobel , Bernard Agwanda , Ying Bai , Robert F. Breiman

DOI: 10.1371/JOURNAL.PNTD.0003608

关键词: Bartonella InfectionHuman pathogenZoologyEpidemiologyLemniscomys striatusBartonellaHost (biology)MuridaeMastomysBiology

摘要: Several rodent-associated Bartonella species are human pathogens but little is known about their epidemiology. We trapped rodents and shrews around habitations at two sites in Kenya (rural Asembo urban Kibera) to determine the prevalence of infection. were detected by culture five seven host species. In Kibera, 60% Rattus rattus positive, as compared 13% Asembo. also C. olivieri (7%), Lemniscomys striatus (50%), Mastomys natalensis (43%) R. norvegicus (50%). Partial sequencing citrate synthase (gltA) gene isolates showed that Kibera strains similar reference from Asia, America, Europe, most less similar. Host trapping location associated with differences infection status there was no evidence associations between age or sex status. Acute febrile illness occurs high incidence both etiology many these illnesses unknown. small mammals investigation ecological determinants public health significance infections locations warranted.

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