Development of composite PLGA microspheres containing exenatide-encapsulated lecithin nanoparticles for sustained drug release.

作者: Ni Dong , Chune Zhu , Junhuang Jiang , Di Huang , Xing Li

DOI: 10.1016/J.AJPS.2019.01.002

关键词: Subcutaneous injectionArea under the curveNanoparticleCytotoxicityPharmacokineticsChemistryPLGALecithinChromatographyBiocompatibility

摘要: … PLGA microspheres. Compared to Ms prepared by the conventional water-in-oil-in-water (W/O/W) technique (Ex-PLGA-Ms), Ex-NPs-PLGA-… spherical shapes (Fig. 2A) compared to Ex-…

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