Nanoparticles for Photodynamic Therapy of Cancer

摘要: The sections in this article are Introduction Concept and Basis of Photodynamic Therapy Photodetection Mechanisms Photodiagnosis Selective Tumor Uptake Photosensitizers Photosensitizers Conventional Photosensitizers New Entities Photodynamic Therapy: Advantages Limitations Photosensitizer Formulations Non-biodegradable Nanoparticles for Therapy Metallic Nanoparticles Ceramic Nanoparticles Nanoparticles Made Non-biodegradable Polymers Biodegradable Polymeric Therapy Preparation Biodegradable Nanoparticles In situ Polymerization Dispersion a Preformed Polymer “Stealth” Particles Targeted Nanoparticles In Vitro Relevance PDT on Cell Models Photodynamic Activity PS-loaded Nanoparticles Uptake Trafficking Photosensitizers In Vivo PDT Biodistribution Pharmacokinetics Photosensitizers Coupled to Nanoparticles Vascular Effects In Efficacy Tumor: Suppression Effects Adverse Effects Conclusions Acknowledgments