作者: Sam Al-Sohaily , Andrew Biankin , Rupert Leong , Maija Kohonen-Corish , Janindra Warusavitarne
DOI: 10.1111/J.1440-1746.2012.07200.X
关键词: Genetics 、 Colorectal cancer 、 Microsatellite instability 、 Genome instability 、 Cancer research 、 Cancer 、 Chromosome instability 、 Germline mutation 、 Genetic predisposition 、 CpG Island Methylator Phenotype 、 Biology
摘要: … of multiple pathways. Germline … of genetic and epigenetic alterations results in sporadic CRC. This review aims to discuss the genetic basis of hereditary CRC and the different pathways …