Molecular pathways in colorectal cancer

作者: Sam Al-Sohaily , Andrew Biankin , Rupert Leong , Maija Kohonen-Corish , Janindra Warusavitarne

DOI: 10.1111/J.1440-1746.2012.07200.X

关键词: GeneticsColorectal cancerMicrosatellite instabilityGenome instabilityCancer researchCancerChromosome instabilityGermline mutationGenetic predispositionCpG Island Methylator PhenotypeBiology

摘要: … of multiple pathways. Germline … of genetic and epigenetic alterations results in sporadic CRC. This review aims to discuss the genetic basis of hereditary CRC and the different pathways …

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