T Cell Interleukin 1

作者: Scott K. Durum , Alison Finnegan , Dan T. Brody , Elizabeth J. Kovacs , Mark R. Smith

DOI: 10.1007/978-1-4612-4598-8_11

关键词: Interleukin 12Interleukin 5Interleukin 4ChemistryMolecular biologyLymphokine-activated killer cellT cellInterleukin 3Interleukin 21Interleukin 15

摘要: T cells have generally been regarded as targets for interleukin 1 (IL 1) action. However, we recently observed that the D10.G4.1 cell clone, widely used an assay IL (1), produced its own following activation by antigen-presenting B (2). Here extend our observations on 1: The majority of murine clones activity after stimulation 2) This was neutralized anti-IL 1-α antibody 3) mRNA could be visualized in individual cloned using situ hybridization 4) Anti-IL blocked proliferation antigen-stimulated under conditions which sole source.

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