Cutaneous anergy without systemic disease. A syndrome associated with mucocutaneous fungal infection.

摘要: This twenty-one year old girl, in good general health, had cutaneous anergy and a ten history of unusual chronic superficial fungal infections. She gave negative response to common skin tests, her could not be sensitized either actively or passively, through transfer lymphocytes, she diminished skin-homograft rejection. All noncutaneous immunologic parameters were normal, including protein electrophoresis, immunoglobulins, circulating antibodies, lymphocyte count stimulation with phytohemagglutinin. Her immediate family normal responses. It is suggested that both infections resulted from an underlying defect dermal reactivity resistance, on dermatologic basis. may represent the first documented case without systemic disease, syndrome would have clinical significance. Cutaneous interpreted as nonspecific finding occur subjects, disease spectrum abnormalities.