Ductular reaction and its diagnostic significance.

摘要: Ductular reaction refers to an increased number of ductules (the finest ramifications the biliary tree), accompanied by polymorphonuclear leukocytes and increase in matrix, leading periportal fibrosis eventually cirrhosis. It is a phenomenon that seen variety liver diseases, such as acute chronic cholestasis variable degrees parenchymal necrosis. has gained new interest because its relationship with putative human progenitor cells. The existence cells quiescent organ liver, although still controversial, important for understanding biological processes, embryogenesis, carcinogenesis, regeneration. This article provides diagnostic algorithm: Starting from ductular reaction, portal tract changes give clues are systematically described.