IL-1 Can Act as Number One
作者： Ana M. Gamero , Joost J. Oppenheim
DOI: 10.1016/J.IMMUNI.2005.12.007
关键词: Cell biology 、 Adapter (genetics) 、 Receptor 、 Biology 、 TLR2
摘要: Both interleukin-1 receptor (IL-1R) and toll-like 2 (TLR2) signal via the adapter molecule MyD88. However, in response to a cutaneous infection challenge, downstream signaling events diverge IL-1R, but not TLR2, proves be essential for host defense.
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