Clustering of cerebral cortical lesions in patients with corticobasal degeneration
作者： R.A Armstrong , N.J Cairns , P.L Lantos
DOI: 10.1016/S0304-3940(99)00309-2
关键词: Corticobasal degeneration 、 Pia mater 、 Lewy body 、 Cortex (anatomy) 、 Biology 、 Cerebral cortex 、 Neuroscience 、 Tau protein 、 Temporal cortex 、 Central nervous system
摘要: Clustering of ballooned neurons (BN) and tau positive with inclusion bodies (tau+ neurons) was studied in the upper lower laminae frontal, parietal temporal cortex 12 patients corticobasal degeneration (CBD). In a significant proportion brain areas examined, BN tau+ exhibited clustering regular distribution clusters parallel to pia mater. A pattern observed equally frequently all cortical examined laminae. No correlations were between cluster sizes or compared neurons. The results suggest that CBD exhibit same type spatial as lesions Alzheimer's disease, Lewy body dementia Pick's disease. periodicity cerebral is consistent cortico-cortical projections CBD.
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