Dibenzopyridoimidazocinnolinium cations: a new family of light-up fluorescent DNA probes

作者: Pedro Bosch , David Sucunza , Francisco Mendicuti , Alberto Domingo , Juan J. Vaquero

DOI: 10.1039/C8QO00236C

关键词: ChemistryBiophysicsDNAHybridization probeConfocal microscopyCircular dichroismIntercalation (chemistry)StainingCoupling reactionFluorescence

摘要: … MeOH) and affinity for DNA (binding … fluorescence probes for DNA, although its fluorescence intensity, as in most azonia derivatives, 6,15 is quenched upon complex formation with DNA …

参考文章(67)
Andrey S. Klymchenko, Yves. Mely, Fluorescent environment-sensitive dyes as reporters of biomolecular interactions. Progress in Molecular Biology and Translational Science. ,vol. 113, pp. 35- 58 ,(2013) , 10.1016/B978-0-12-386932-6.00002-8
Nina Berova, Robert W. Woody, 香爾 中西, Circular Dichroism: Principles and Applications ,(1994)
Yun Xie, Victor K. Tam, Yitzhak Tor, The Interactions of Small Molecules with DNA and RNA The Chemical Biology of Nucleic Acids. pp. 115- 140 ,(2010) , 10.1002/9780470664001.CH6
Alberto Abengózar, Beatriz Abarca, Ana M. Cuadro, David Sucunza, Julio Álvarez-Builla, Juan J. Vaquero, Azonia Aromatic Cations by Ring‐Closing Metathesis: Synthesis of Azaquinolizinium Cations European Journal of Organic Chemistry. ,vol. 2015, pp. 4214- 4223 ,(2015) , 10.1002/EJOC.201500404
Roberta Bortolozzi, Heiko Ihmels, Laura Thomas, Maoqun Tian, Giampietro Viola, 9‐(4‐Dimethylaminophenyl)benzo[b]quinolizinium: A Near‐Infrared Fluorophore for the Multicolor Analysis of Proteins and Nucleic Acids in Living Cells Chemistry: A European Journal. ,vol. 19, pp. 8736- 8741 ,(2013) , 10.1002/CHEM.201301164
S. Bolte, C. Talbot, Y. Boutte, O. Catrice, N. D. Read, B. Satiat-Jeunemaitre, FM-dyes as experimental probes for dissecting vesicle trafficking in living plant cells. Journal of Microscopy. ,vol. 214, pp. 159- 173 ,(2004) , 10.1111/J.0022-2720.2004.01348.X
Hisataka Kobayashi, Mikako Ogawa, Raphael Alford, Peter L. Choyke, Yasuteru Urano, New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging Chemical Reviews. ,vol. 110, pp. 2620- 2640 ,(2010) , 10.1021/CR900263J
Ana Nuñez, Beatriz Abarca, Ana M. Cuadro, Julio Alvarez-Builla, Juan J. Vaquero, Ring‐Closing Metathesis Approach to Heteroaromatic Cations: Synthesis of Benzo[a]quinolizinium Salts European Journal of Organic Chemistry. ,vol. 2011, pp. 1280- 1290 ,(2011) , 10.1002/EJOC.201001373
Serena Basili, Anna Bergen, Francesco Dall'Acqua, Anita Faccio, Anton Granzhan, Heiko Ihmels, Stefano Moro, Giampietro Viola, Relationship between the structure and the DNA binding properties of diazoniapolycyclic duplex- and triplex-DNA binders: efficiency, selectivity, and binding mode. Biochemistry. ,vol. 46, pp. 12721- 12736 ,(2007) , 10.1021/BI701518V
Tasuku Ueno, Tetsuo Nagano, Fluorescent probes for sensing and imaging Nature Methods. ,vol. 8, pp. 642- 645 ,(2011) , 10.1038/NMETH.1663