Cross-Reactive T-Cell Antigens among Mammalian Species

摘要: Fluoresceinated heteroantisera prepared against T cells of rats, monkeys, and humans were reacted with thymus spleen from 11 selected species. These reagents recognized cross-reacting cell antigen(s) among rodent species (mouse, rat, guinea pig, hamster) primate (monkey humans). With one exception, the cross-reactivity was restricted to a phylogenetic order. All three antisera required relatively few absorptions achieve specificity for related when compared absorption requirements isologous Differentiation antigens within order thus appear be more homologous than other surface constituents on cells.