Transcranial magnetic stimulation on the modulation of gamma oscillations in schizophrenia.

作者: Faranak Farzan , Mera S. Barr , Yinming Sun , Paul B. Fitzgerald , Zafiris J. Daskalakis

DOI: 10.1111/J.1749-6632.2012.06543.X

关键词: Prefrontal cortexPsychologyNeuroscienceCognitionSchizophreniaEffects of sleep deprivation on cognitive performanceElectroencephalographyCortex (anatomy)Transcranial magnetic stimulationDorsolateral prefrontal cortex

摘要: Cognitive dysfunction is suggested to be the best predictor of functional outcome in schizophrenia. Therefore, new diagnostic and treatment strategies are needed both ascertain biological underpinning cognitive deficits restore them. Modulation gamma oscillations (30-50 Hz) has been associated with performance, particularly dorsolateral prefrontal cortex (DLPFC). In this manuscript, we review evidence for modulation during performance We demonstrate that transcranial magnetic stimulation (TMS) combined electroencephalography (EEG) a reliable method permits systematic quantification cortex. Using TMS-EEG, show patients schizophrenia have selective inhibition DLPFC. Finally, repetitive TMS therapy over DLPFC can normalize excessive ultimately patients. suggest restoring impairments may potential strategy improving

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