Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

作者: Janaiah Kota , Raghu R. Chivukula , Kathryn A. O'Donnell , Erik A. Wentzel , Chrystal L. Montgomery

DOI: 10.1016/J.CELL.2009.04.021

关键词: ApoptosisLiver cancermicroRNAHepatocellular carcinomaCarcinogenesisSystemic administrationBiologyCyclinGene silencingCancer research

摘要: … Consistent with our earlier demonstration that expression of miR-26a arrests the cell cycle in HepG2 cells, we observed markedly reduced Ki67 staining in tumors following …

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