microRNAs exhibit high frequency genomic alterations in human cancer

作者: L. Zhang , J. Huang , N. Yang , J. Greshock , M. S. Megraw

DOI: 10.1073/PNAS.0508889103

关键词: Gene dosageCancerGeneticsmicroRNAGene expression profilingGeneGene silencingComparative genomic hybridizationBiologyCopy-number variation

摘要: MicroRNAs (miRNAs) are endogenous noncoding RNAs, which negatively regulate gene expression. To determine genomewide miRNA DNA copy number abnormalities in cancer, …

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