Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs

作者: David P. Bartel , Chang-Zheng Chen

DOI: 10.1038/NRG1328

关键词: GenemicroRNACell typeGene expressionBiologyGene silencingGeneticsComputational biologyRNA interferenceRegulation of gene expressionHuman genome

摘要: … genes and the miRNA genes. In summary, the post-transcriptional dampening of gene expression by miRNAs offers both a mechanism for more uniform gene expression for cells of a …

参考文章(44)
Gary Ruvkun, Brenda J. Reinhart, Frank J. Slack, Michael Basson, Amy E. Pasquinelli, Jill C. Bettinger, Ann E. Rougvie, H. Robert Horvitz, The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans Nature. ,vol. 403, pp. 901- 906 ,(2000) , 10.1038/35002607
Amy E Pasquinelli, Brenda J Reinhart, Frank Slack, Mark Q Martindale, Mitzi I Kuroda, Betsy Maller, David C Hayward, Eldon E Ball, Bernard Degnan, Peter Müller, Jürg Spring, Ashok Srinivasan, Mark Fishman, John Finnerty, Joseph Corbo, Michael Levine, Patrick Leahy, Eric Davidson, Gary Ruvkun, None, Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA Nature. ,vol. 408, pp. 86- 89 ,(2000) , 10.1038/35040556
Mariana Lagos-Quintana, Reinhard Rauhut, Abdullah Yalcin, Jutta Meyer, Winfried Lendeckel, Thomas Tuschl, Identification of tissue-specific microRNAs from mouse Current Biology. ,vol. 12, pp. 735- 739 ,(2002) , 10.1016/S0960-9822(02)00809-6
Lee P Lim, Margaret E Glasner, Soraya Yekta, Christopher B Burge, David P Bartel, Vertebrate microRNA genes. Science. ,vol. 299, pp. 1540- 1540 ,(2003) , 10.1126/SCIENCE.1080372
Matthew W. Rhoades, Brenda J. Reinhart, Lee P. Lim, Christopher B. Burge, Bonnie Bartel, David P. Bartel, Prediction of Plant MicroRNA Targets Cell. ,vol. 110, pp. 513- 520 ,(2002) , 10.1016/S0092-8674(02)00863-2
Juan E. Abrahante, Aric L. Daul, Ming Li, Mandy L. Volk, Jason M. Tennessen, Eric A. Miller, Ann E. Rougvie, The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Developmental Cell. ,vol. 4, pp. 625- 637 ,(2003) , 10.1016/S1534-5807(03)00127-8
Hristo B Houbaviy, Michael F Murray, Phillip A Sharp, Embryonic Stem Cell-Specific MicroRNAs Developmental Cell. ,vol. 5, pp. 351- 358 ,(2003) , 10.1016/S1534-5807(03)00227-2
R. C. Lee, An Extensive Class of Small RNAs in Caenorhabditis elegans Science. ,vol. 294, pp. 862- 864 ,(2001) , 10.1126/SCIENCE.1065329
Bonnie Bartel, David P. Bartel, MicroRNAs: at the root of plant development? Plant Physiology. ,vol. 132, pp. 709- 717 ,(2003) , 10.1104/PP.103.023630