MicroRNAs: New Players in AML Pathogenesis
作者： Milena S. Nicoloso , Bharti Jasra , George A. Calin
DOI: 10.1007/978-0-387-69259-3_10
关键词:
摘要: MicroRNAs (miRNAs) constitute a class of regulatory non-coding RNAs involved in gene silencing pathways. They are single-stranded RNA molecules ranging from 19 to 25 nucleotides and may be considered the natural counterparts small interfering (siRNAs). Because their fine regulation expression at post-transcriptional level, miRNAs crucial players several pathways, including developmental timing, organogenesis, differentiation, hematopoiesis, apoptosis, cell proliferation, tumorigenesis [2]. The network miRNA messenger (mRNA) is combinatorial unique each type; fact, single molecule can bind repress different mRNAs multiple cooperate control mRNA target, cell-customized manner [33]. pleiotropic potential, also cellular micromanagers [2, 33]
springer.com
elsevier.com
sci-hub.st 参考文章(49)
Kristina L. Rhoades, Christopher J. Hetherington, Nari Harakawa, Donald A. Yergeau, Liming Zhou, Li-Qin Liu, Marie-Terese Little, Daniel G. Tenen, Dong-Er Zhang, Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model Blood. ,vol. 96, pp. 2108- 2115 ,(2000) , 10.1182/BLOOD.V96.6.2108
Erik J Sontheimer, Richard W Carthew, Argonaute Journeys into the Heart of RISC Science. ,vol. 305, pp. 1409- 1410 ,(2004) , 10.1126/SCIENCE.1103076
David P. Bartel, Chang-Zheng Chen, Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs Nature Reviews Genetics. ,vol. 5, pp. 396- 400 ,(2004) , 10.1038/NRG1328
Aurora Esquela-Kerscher, Frank J. Slack, Oncomirs — microRNAs with a role in cancer Nature Reviews Cancer. ,vol. 6, pp. 259- 269 ,(2006) , 10.1038/NRC1840
Silvia Monticelli, K Mark Ansel, Changchun Xiao, Nicholas D Socci, Anna M Krichevsky, To-Ha Thai, Nikolaus Rajewsky, Debora S Marks, Chris Sander, Klaus Rajewsky, Anjana Rao, Kenneth S Kosik, MicroRNA profiling of the murine hematopoietic system Genome Biology. ,vol. 6, pp. 1- 15 ,(2005) , 10.1186/GB-2005-6-8-R71
R Garzon, F Pichiorri, T Palumbo, M Visentini, R Aqeilan, A Cimmino, H Wang, H Sun, S Volinia, H Alder, G A Calin, C-G Liu, M Andreeff, C M Croce, MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia Oncogene. ,vol. 26, pp. 4148- 4157 ,(2007) , 10.1038/SJ.ONC.1210186
Unnur Thorsteinsdottir, Aline Mamo, Evert Kroon, Lori Jerome, Janet Bijl, H. Jeffrey Lawrence, Keith Humphries, Guy Sauvageau, Overexpression of the myeloid leukemia–associatedHoxa9 gene in bone marrow cells induces stem cell expansion Blood. ,vol. 99, pp. 121- 129 ,(2002) , 10.1182/BLOOD.V99.1.121
Yoontae Lee, Chiyoung Ahn, Jinju Han, Hyounjeong Choi, Jaekwang Kim, Jeongbin Yim, Junho Lee, Patrick Provost, Olof Rådmark, Sunyoung Kim, V. Narry Kim, The nuclear RNase III Drosha initiates microRNA processing Nature. ,vol. 425, pp. 415- 419 ,(2003) , 10.1038/NATURE01957
A. Cimmino, G. A. Calin, M. Fabbri, M. V. Iorio, M. Ferracin, M. Shimizu, S. E. Wojcik, R. I. Aqeilan, S. Zupo, M. Dono, L. Rassenti, H. Alder, S. Volinia, C.-g. Liu, T. J. Kipps, M. Negrini, C. M. Croce, miR-15 and miR-16 induce apoptosis by targeting BCL2. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 102, pp. 13944- 13949 ,(2005) , 10.1073/PNAS.0506654102
F. Kuchenbauer, M. Feuring–Buske, C. Buske, AML1-ETO needs a partner: new insights into the pathogenesis of t(8;21) leukemia. Cell Cycle. ,vol. 4, pp. 1716- 1718 ,(2005) , 10.4161/CC.4.12.2256