Reactive triblock copolymer micelles induced by click reaction: A platform for RAFT polymerization
作者： Jie Jin , Jia Tian , Xueming Lian , Pingchuan Sun , Hanying Zhao
DOI: 10.1039/C1SM06225E
关键词: Chain transfer 、 Reversible addition−fragmentation chain-transfer polymerization 、 Polymerization 、 Copolymer 、 Micelle 、 Polymer chemistry 、 Raft 、 Chemistry 、 Azide 、 Polymer
摘要: In this manuscript in situRAFT polymerization inside reactive triblock copolymer micelles were reported. Poly(ethylene glycol)-block-poly(2-hydroxyethyl methacrylate)-block-poly(tert-butyl acrylate) (PEG-b-PHEMA-b-PtBA) was synthesized through two-step ATRP of HEMA and tBA by using initiator terminated PEG as macroinitiator. The pendant azide groups introduced to the short mid-blocks reactions with 2-bromoisobutyryl bromide sodium azide, respectively. Click reaction between azido-modified dialkynetrithiocarbonate results formation cross-linked cores PtBA/PEG coronae. size micellar aggregates is determined initial polymer concentration. entrapped reversible addition-fragmentation chain transfer (RAFT) agent molecules used RAFT N-isopropylacrylamide (NIPAM). After polymerization, polymeric PNIPAM PEG/PtBA coronae obtained. FTIR, 1H NMR, dynamic light scattering transmission electron microscopy characterize structures before after polymerization. degradation also investigated research. This type can be a platform for
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