Low-abundance drug-resistant viral variants in chronically HIV-infected, antiretroviral treatment-naive patients significantly impact treatment outcomes.

作者： Birgitte B. Simen , Jan Fredrik Simons , Katherine Huppler Hullsiek , Richard M. Novak , Rodger D. MacArthur

关键词: Oncology 、 Virology 、 Viral disease 、 Regimen 、 Proportional hazards model 、 Drug resistance 、 Confidence interval 、 Acquired immunodeficiency syndrome (AIDS) 、 Hazard ratio 、 Biology 、 Internal medicine 、 Sida

摘要: … Upon review, we concluded that the mutations had been detected with ultra-deep sequencing (one sample with K103N at 54% and the second sample with 69D/N at 22%/45%), but …

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Low-abundance drug-resistant viral variants in chronically HIV-infected, antiretroviral treatment-naive patients significantly impact treatment outcomes.

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Low-abundance drug-resistant viral variants in chronically HIV-infected, antiretroviral treatment-naive patients significantly impact treatment outcomes.

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