Functional diversity of helper T lymphocytes.

作者: Abul K. Abbas , Kenneth M. Murphy , Alan Sher

DOI: 10.1038/383787A0

关键词: Self ToleranceCytokineImmunologyT lymphocyteCellular differentiationCytokine secretionHelper T lymphocyteAutoimmunityBiologyImmune system

摘要: The existence of subsets CD4+ helper T lymphocytes that differ in their cytokine secretion patterns and effector functions provides a framework for understanding the heterogeneity normal pathological immune responses. Defining cellular molecular mechanisms helper-T-cell differentiation should lead to rational strategies manipulating responses prophylaxis therapy.

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