作者: Abul K. Abbas , Kenneth M. Murphy , Alan Sher
DOI: 10.1038/383787A0
关键词: Self Tolerance 、 Cytokine 、 Immunology 、 T lymphocyte 、 Cellular differentiation 、 Cytokine secretion 、 Helper T lymphocyte 、 Autoimmunity 、 Biology 、 Immune system
摘要: The existence of subsets CD4+ helper T lymphocytes that differ in their cytokine secretion patterns and effector functions provides a framework for understanding the heterogeneity normal pathological immune responses. Defining cellular molecular mechanisms helper-T-cell differentiation should lead to rational strategies manipulating responses prophylaxis therapy.