Stereocontrolled Synthesis of Enantiopure Substituted 4‐Aminopyrrolidin‐2‐ones.
作者： N. LANGLOIS , O. CALVEZ , M.-O. RADOM
关键词: Conjugate 、 Chemistry 、 Pyrrole derivatives 、 Lactam 、 Benzylamine 、 Stereochemistry 、 Organic chemistry 、 Enantiopure drug
摘要: Abstract The highly diastereoselective conjugate addition of N -benzylhydroxylamine and benzylamine to α,β-unsaturated lactam 3 provided an efficient entry enantiopure (4 S ,5 )-4-amino-5-hydroxymethylpyrrolidin-2-ones. © 1997 Elsevier Science Ltd.
sci-hub.se 参考文章(1)
Nicole Langlois, Olivier Calvez, Marie-Odile Radom, Stereocontrolled Synthesis of Enantiopure Substituted 4-Aminopyrrolidin-2-ones Tetrahedron Letters. ,vol. 38, pp. 8037- 8040 ,(1997) , 10.1016/S0040-4039(97)10216-7