Inhaled and exhaled nitric oxide.

摘要: Inhaled nitric oxide (NO) is used to treat various cardiopulmonary disorders associated with pulmonary hypertension. The rationale based on the fact that NO, given by inhalation, only dilates those vessels perfuse well-ventilated lung units. As a result, gas exchange improved while vascular resistance reduced and blood flow increased. NO has been successfully applied persistent hypertension of newborn, reducing need for extracorporeal life support. Although altered vasoreactivity contribute profound hypoxaemia in adult paediatric acute respiratory distress syndrome (ARDS), benefit inhaled still remains be established patients ARDS. ARDS complex response direct or indirect insults, leading vasoconstriction inflammatory responses. Recent randomized trials suggest causes transient improvement oxygenation. Whether this effect important long-term management established. measured exhaled breath, an elegant non-invasive means monitor inflammation upper lower tract. In normal airways, bulk originates from paranasal sinuses. Exhaled increased nasal allergy decreased cystic fibrosis, polyposis chronic sinusitis. That production asthmatic airways also well However, several questions addressed, particular evaluation sensitivity specificity measurement techniques, assessment bronchodilator action endogenous NO.