Dual targeting of epigenetic therapy in cancer

作者: Debby M.E.I. Hellebrekers , Arjan W. Griffioen , Manon van Engeland

DOI: 10.1016/J.BBCAN.2006.07.003

关键词: HDAC11Histone deacetylase inhibitorCancer epigeneticsEpigenetic therapyCancer researchHistone deacetylaseDNA methylationBiologyHistone deacetylase 5Epigenetics

摘要: … By reactivation of epigenetically silenced … epigenetic promoter modifications in endothelial cells treated with DNMT and HDAC inhibitors. Clearly, the dual targeting of epigenetic therapy …

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