Outcome for triple negative breast cancer in a retrospective cohort with an emphasis on response to platinum-based neoadjuvant therapy

作者: Elaine M. Walsh , Aliaa Shalaby , Mark O’Loughlin , Nessa Keane , Mark J Webber

DOI: 10.1007/S10549-018-5066-6

关键词: OncologyRetrospective cohort studyMedicineBreast cancerInternal medicineTriple-negative breast cancerComplete responseNeoadjuvant therapyPathologicalCarboplatinChemotherapy

摘要: Purpose The rate of pathological complete response (pCR) for patients with triple negative breast cancer (TNBC) is increased when carboplatin added to neo-adjuvant chemotherapy (NACT). However, while phase III trial data showing a survival benefit are awaited, not yet standard-of-care TNBC. The aim this study was examine the pCR and outcome those treated predictors therapy.

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