Origins and consequences of antimicrobial-resistant nontyphoidal Salmonella: implications for the use of fluoroquinolones in food animals.

摘要: Human Salmonella infections are common; most self-limiting, however severe disease may occur. Antimicrobial agents, while not essential for the treatment of gastroenteritis, thousands patients each year with invasive infections. Fluoroquinolones and third-generation cephalosporins drugs-of-choice in humans; alternative antimicrobial choices limited by increasing resistance, efficacy, less desirable pharmacodynamic properties. Antimicrobial-resistant results from use agents food animals, these resistant subsequently transmitted to humans, usually through supply. The resistance patterns isolates collected persons show more used agriculture than humans. Because adverse health consequences humans animals associated prevalence antimicrobial-resistant Salmonella, there is an urgent need emphasize non-antimicrobial infection control strategies, such as improved sanitation hygiene, develop guidelines prudent usage establishment adequate public safeguards minimize development dissemination agents.